Publications:

- Peer-Reviewed Journal Articles (citations: 1891, h-index: 23, i10-index: 29)
62. Han, S.P., Bigdelou, P., Kajiuchi, T., and Lee, M.Y., Lipase modified with hydrophobic polymers and its characteristics, In preparation for submission (2018)
61. Bigdelou, P., Yu, K.N., Tang, J.S., Whited, J., Wang, D., Sun, X.L., and Lee, M.Y., Modulation of mouse macrophages on a microarray chip with synthetic glycopolymers, In preparation for submission (2018)
60. Yu, K.N., Kang, S.Y., and Lee, M.Y., Incorporating high-throughput metabolism-induced toxicity assays on a 384-pillar plate, In preparation for submission (2018)
59. Lee, D.W., Kang, J.H., Yeon, S.E., Ku, B.S., Lee, M.Y., and Kuh, H.J., High-throughput, high-content histological analysis of three-dimensional tumor spheroids by using a pillar array chip, Lab on a Chip, Submitted (2018)
58. Joshi, P., Datar, A., Yu, K.N., Kang, S.Y., and Lee, M.Y., High-content imaging assays on a miniaturized 3D cell culture platform, Toxicology In Vitro, Submitted (2018)
57. Roth, A.D., Lama, P., Dunn, S., Hong, S., and Lee, M.Y., Polymer coating on a micropillar chip for robust attachment of PuraMatrix peptide hydrogel for 3D hepatic cell culture, Materials Science and Engineering C, Accepted (2017)
56. Farrell, K., Mahajan, G., Srinivasan, P., Lee, M.Y., and Kothapalli, C.R., Pediatric glioblastoma cells inhibit neurogenesis and promote astrogenesis, phenotypic transformation and migration of human neural progenitor cells within cocultures, Experimental Cell Research, Accepted (2017)
55. Yu, S., Joshi, P., Park, Y.J., Yu, K.N., and Lee, M.Y., Deconvolution of images from 3D printed cells in layers on a chip, Biotechnology Progress, Accepted (2017)
54. Yu, K.N., Nadanaciva, S.N., Rana, P., Lee, D.W., Ku, B.S., Roth, A.D., Dordick, J.S., Will, Y., and Lee, M.Y., Prediction of metabolism-induced hepatotoxicity on three-dimensional hepatic cell culture and enzyme microarrays, Archives of Toxicology, doi.org/10.1007/s00204-017-2126-3 (2017)
53. Lee, M.Y., Bigdelou, P., Hong, K.J., Kim, K.A., Shinya, Y., and Kajiuchi, T., Peroxidase chemically attached on polymeric micelle and its reaction with phenolic compounds, Enzyme and Microbial Technology, 109, 43-50 (2017)
52. Roth, A.D. and Lee, M.Y., Idiosyncratic drug-induced liver injury (IDILI): Mechanisms and predictive assays, BioMed Research International, DOI:10.1155/2017/9176937, Article ID 9176937, 23 pages (2017)
51. Lee, D.W., Oh, W.Y., Yi, S.H., Ku, B.S., Lee, M.Y., Cho, Y.H., and Yang, M.H., Estimation of bisphenol A - Human toxicity by 3D cell culture arrays, high throughput alternatives to animal tests, Toxicology Letters, 259, 87-94 (2016)
50. Kang, J.H., Lee, D.W., Hwang, H.J., Yeon, S.E., Lee, M.Y., and Kuh, H.J., Mini-pillar array for hydrogel-supported 3D culture and high-content histologic analysis of human tumor spheroids, Lab on a Chip, DOI: 10.1039/c6lc00526h (2016)
49. Sameera, T., Farrell, K., Lee, M.Y., and Kothapalli, C.R., Sensitivity of neural stem cell survival, differentiation and neurite outgrowth within 3D hydrogels to environmental heavy metals, Toxicology Letters, 242, 9-22 (2016)
48. Joshi, P. and Lee, M.Y., High content imaging (HCI) on miniaturized three-dimensional (3D) cell cultures, Biosensors, 5, 768-790 (2015)
47. Datar, A., Joshi, P., and Lee, M.Y., Biocompatible hydrogels for microarray cell printing and encapsulation, Biosensors, 5, 647-663 (2015)
46. Lee, D.W., Lee, M.Y., Ku, B.S., and Nam, D.H., Automatic 3D cell analysis in high-throughput microarray using micropillar and microwell chips, Journal of Biomolecular Screening, 20(9), 1178-1184 (2015)
45. Lee, D.W., Choi, Y.S., Seo, Y.J., Lee, M.Y., Jeon, S.Y., Ku, B.S., Kim, S.J., Yi, S.H., and Nam, D.H., High-throughput, miniaturized clonogenic assay on a micropillar/microwell chip with brain tumor cells isolated from patients, Small, 10(24), 5098-5105 (2014)
44. Kwon, S.J., Lee, D.W., Shah, D.A., Ku, B.S., Jeon, S.Y., Solanki, K., Ryan, J.D., Clark, D.S., Dordick, J.S., and Lee, M.Y., High-throughput and combinatorial gene expression on a chip for metabolism-induced toxicology screening, Nature Communications, 5:3739 DOI: 10.1038/ncomms4739 (2014)
43. Lee, M.Y., Hong, K.J., Han, S.P., and Kajiuchi, T., Enzyme attached on polymeric micelles as a nanoscale reactor, Korean Journal of Chemical Engineering, 31(2), 188-193 (2014)
42. Lee, D.W., Choi, Y.S., Seo, Y.J., Lee, M.Y.,  Jeon, S.Y., Ku, B.S., Kim, S.J., Yi, S.H., and Nam, D.H., High-throughput screening (HTS) of anticancer drug efficacy on a micropillar/microwell chip platform, Analytical Chemistry, 86(1), 535-542 (2014)
41. Lee, D.W., Lee, M.Y., Ku, B.S., Yi, S.H., Ryu, J.H., Jeon, R., and Yang, M.H., Application of the DataChip/MetaChip technology for the evaluation of ajoene toxicity in vitro, Archives of Toxicology, 88(2), 283-290 (2014) [DWL and MYL contributed equally to this work]
40. Lee, D.W., Yi, S.H, Jeong, S.H., Ku, B.S., Kim, J.G., and Lee, M.Y., Plastic pillar inserts for three-dimensional (3D) cell cultures in 96-well plates, Sensors and Actuators B, 177(1), 78-85 (2013)
39. Zhang, H.Y., Lee, M.Y., Hogg, M.G., Dordick, J.S., and Sharfstein, S.T., High-throughput transfection of interfering RNA into a three-dimensional cell-culture chip, Small, 8(13), 2091-2098 (2012)
38. Kwon, S.J., Mora-Pale, M., Lee, M.Y., and Dordick, J.S., Expanding nature┬┐s small molecule diversity via in vitro biosynthetic pathway engineering, Current Opinion in Chemical Biology, 16, 186-195 (2012)
37. Zhang, H.Y., Lee, M.Y., Hogg, M.G., Dordick, J.S., and Sharfstein, S.T., Gene delivery in three-dimensional cell cultures by superparamagnetic nanoparticles, ACS nano, 4(8), 4733-4743 (2010)
36. Fernandes, T.G., Kwon, S.J., Lee, M.Y., Diogo, M.M., Clark, D.S., Cabral, J.M.S., and Dordick, J.S., Three-dimensional cell culture microarray for high-throughput studies of stem cell fate, Biotechnology and Bioengineering, 106, 106-118 (2010)
35. Sukumaran, S.M., Potsaid, B., Lee, M.Y., Clark, D.S., and Dordick, J.S., Development of a fluorescence-based, ultra high-throughput screening platform for nanoliter-scale cytochrome P450 microarrays, Journal of Biomolecular Screening, 14(6), 668-678 (2009)
34. Park, T.J., Lee, M.Y., Dordick, J.S. and Linhardt, R.J., Signal amplification of target protein on heparin glycan microarray, Analytical Biochemistry, 383, 116-121 (2008) [TJP and MYL contributed equally to this work]
33. Fernandes, T.G., Kwon, S.J., Lee, M.Y., Clark, D.S., Cabral, J.M.S. and Dordick, J.S., On-chip, cell-based microarray immunofluorescence assay for high-throughput analysis of target proteins, Analytical Chemistry, 80, 6633-6639 (2008)
32. Lee, M.Y., Ramasubramanian, A.K., Sukumaran, S., Hogg, M., Clark, D.S. and Dordick, J.S., Three-dimensional cellular microarray for microscale toxicology assay, Proceedings of the National Academy of Sciences of the United States of America (PNAS), 105(1), 59-63 (2008) [Highlighted in a front section of the print journal called 'In this issue']  
31. Kwon, S.J., Lee, M.Y., Ku, B.S., Sherman D.H. and Dordick, J.S., High-throughput, microarray-based synthesis of natural product analogues via in vitro metabolic pathway construction, ACS Chemical Biology, 2(6), 419-425 (2007)
30. Lee, M.Y. and Dordick, J.S., High-throughput human metabolism and toxicity analysis, Current Opinion in Biotechnology, 17, 619-627 (2006)
29. Lee, M.Y., Clark, D.S. and Dordick, J.S., Human P450 microarrays for in vitro metabolite toxicity analysis: Toward complete automation of human toxicology screening, Journal of the Association for Laboratory Automation, 11(6), 374-380 (2006)
28. Lee, M.Y., Park, C.B., Clark, D.S. and Dordick, J.S., Metabolizing enzyme toxicology assay chip (MetaChip) for high-throughput microscale toxicity analyses, Proceedings of the National Academy of Sciences of the United States of America (PNAS), 102(4), 983-987 (2005) [Featured as cover article]  
27. Lee, M.Y., Hong, K.J., Kajiuchi, T. and Yang, J.W., Synthesis of chitosan-based polymeric surfactants and their adsorption properties for heavy metals and fatty acids, International Journal of Biological Macromolecules, 36(3), 152-158 (2005)
26. Lee, M.Y., Hong, K.J., Sudo, S. and Kajiuchi, T., Adsorption of hexavalent chromium by chitosan-based polymeric surfactants, Journal of Applied Polymer Science, 96(1), 44-50 (2005)
25. Lee, M.Y., Hong, K.J., Kajiuchi, T. and Yang, J.W., Determination of the efficiency and removal mechanism of cobalt by crab shell particles, Journal of Chemical Technology & Biotechnology, 79(12), 1388-1394 (2004)
24. Shin-ya, Y., Yoshizawa, T., Hong, K.J., Lee, M.Y. and Kajiuchi, T., Log-normal distribution for a description of the molecular weight distribution of N-acetylated chitosans depolymerized with hydrolytic enzyme, Polymer International, 52(5), 838-842 (2003)
23. Lee, M.Y., Srinivasan, A., Ku, B.S. and Dordick, J.S., Multienzyme catalysis in microfluidic biochips, Biotechnology and Bioengineering, 83(1), 20-28 (2003)
22. Srinivasan, A., Wu, X.Q., Lee, M.Y. and Dordick, J.S., Microfluidic peroxidase biochip for polyphenol synthesis, Biotechnology and Bioengineering, 81(5), 563-569 (2003)
21. Lee, M.Y. and Dordick, J.S., Enzyme activation for nonaqueous media, Current Opinion in Biotechnology, 13, 376-384 (2002)
20. Kang, H.A., Jeon, G.J., Lee, M.Y. and Yang, J.W., Effectiveness test of alginate-derived polymeric surfactants, Journal of Chemical Technology & Biotechnology, 77(2), 205-210 (2002)
19. Kang, H.A., Shin, M.S., Lee, M.Y. and Yang, J.W., Characteristics of newly synthesized alginate-derived surfactants, Preprints of Extended Abstracts Presented at the ACS National Meeting, Division of Environmental Chemistry, 41(2), 238-242 (2001)
18. Shin-Ya, Y., Lee, M.Y., Hinode, H. and Kajiuchi, T., Effects of N-acetylation degree on N-acetylated chitosan hydrolysis with commercially available and modified pectinases, Biochemical Engineering Journal, 7(1), 85-88 (2001)
17. Lee, M.Y. and Yang, J.W., Biosorption of cobalt by methanotrophic biomass, Journal of Korean Society of Environmental Engineers, 22(12), 2163-2173 (2001)
16. Lee, M.Y. and Yang, J.W., Biosorption of lead and cobalt by Absidia coerulea and Thraustochitrium sp., Journal of Korean Society of Environmental Engineers, 22(12), 2149-2161 (2001)
15. Kang, H.A., Shin, M.S., Lee, M.Y., Jeon, G.J. and Yang, J.W., Synthesis of alginate-derived polymeric surfactants, Korean Journal of Biotechnology and Bioengineering, 15(4), 375-379 (2000)
14. Lee, M.Y. and Yang, J.W., Characteristics of lead removal by methanotrophic biomass, Korean Journal of Biotechnology and Bioengineering, 15(5), 444-451 (2000)
13. Lee, M.Y., Kang, H.A. and Yang, J.W., Characteristics of lead removal in a fixed-bed column packed with activated carbon and crab shell, Journal of Korean Society of Environmental Engineers, 22(10), 1747-1756 (2000)
12. Lee, M.Y., Cho, H.J. and Yang, J.W., Factors of trichloroethylene degradation by methanotrophic consortium biofilm reactor (MCBR), Journal of Korean Society of Environmental Engineers, 22(6), 991-1000 (2000)
11. Lee, M.Y. and Yang, J.W., Initial condition of methanotrophic consortium biofilm reactor (MCBR) for trichloroethylene degradation, Journal of Korean Society of Environmental Engineers, 22(5), 971-980 (2000)
10. Lee, M.Y., Var, F., Shin-Ya, Y., Kajiuchi, T. and Yang, J.W., Optimum conditions for the precipitation of chitosan oligomer with DP 5-7 in the concentrated hydrochloric acid at low temperature, Process Biochemistry, 34(1), 493-500 (1999)
9. Lee, S.H., Shon, J.S., Chung, H.S., Lee, M.Y. and Yang, J.W., Effect of chemical modification of carboxyl groups in apple residues on metal ion binding, Korean Journal of Chemical Engineering, 16(5), 576-580 (1999)
8. Shin, H.J., Lee, M.Y. and Yang, J.W., Biodegradation of trichloroethylene by phenol-degrading Pseudomonas putida, Journal of Microbiology Biotechnology, 8(2), 185-187 (1998)
7. Lee, M.Y., Lee, S.H., Shin, H.J., Kajiuchi, T. and Yang, J.W., Characteristics of lead removal by crab shell particles, Process Biochemistry, 33(7), 749-753 (1998)
6. Lee, M.Y., Shin, H.J., Lee, S.H., Park, J.M. and Yang, J.W., Removal of lead in a fixed-bed column packed with activated carbon and crab shell, Separation Science and Technology, 33(7), 1043-1056 (1998)
5. Lee, S.H., Jung, C.H., Chung, H.S., Lee, M.Y. and Yang, J.W., Removal of heavy metals from aqueous solution by apple residues, Process Biochemistry, 33(2), 205-211 (1998)
4. Lee, M.Y., Shin, H.J., Yeom, S.P. and Yang, J.W., Biodegradation of trichloroethylene by a methanotrophic consortium, Journal of Korean Society of Environmental Engineers, 20(9), 1207-1217 (1998)
3. Lee, M.Y., Shin, H.J., Yeom, S.P. and Yang, J.W., Isolation and cultivation of methanotrophic consortium for trichloroethylene degradation, Korean Journal of Biotechnology and Bioengineering, 13(5), 483-490 (1998)
2. Lee, M.Y., Park, J.M. and Yang, J.W., Micro precipitation of lead on the surface of crab shell particles, Process Biochemistry, 32(8), 671-677 (1997)
1. Lee, M.Y. and Yang, J.W., Bioremediation of groundwater contaminated by halogenated aliphatic compounds, The Microorganisms & Industry, 21(4), 409-417 (1995)


- Book Chapters
1. Lee, M.Y., Dordick, J.S. and Clark, D.S., Metabolic enzyme microarray coupled with miniaturized cell-culture array technology for high-throughput toxicity screening, Methods in Molecular Biology, 632, 221-237 (2010)
2. Farrel, K., Joshi, P., Roth, A., Kothapalli, C.R., Lee, M.Y., High-throughput screening of toxic chemicals on neural stem cells, Human Stem Cell Toxicology, Royal Society of Chemistry DOI: 10.1039/9781782626787, 31-63 (2016)


- Book
1. Lee, M.Y., Microarray Bioprinting Technology: Fundamentals and Practices, Springer, ISBN # 978-3-319-46803-7 (2016)
- Chapter 1. Overview of microarray bioprinting technology (written by Lee, M.Y.)
- Chapter 2. Microarray spotter and printing technologies (by Datar, A., Lee, D.W., Jeon, S.Y., and Lee, M.Y.)
- Chapter 3. Chip platforms and chip surface treatments (by Bigdelou, P., Roth, A.D., Sichkar, Y., and Lee, M.Y.)
- Chapter 4. Biological sample printing (by Bigdelou, P., Roth, A.D., Datar, A., and Lee, M.Y.)
- Chapter 5. High content cell staining (by Yu, K.N., Joshi, P., and Lee, M.Y.)
- Chapter 6. 3D-Cultured cell image acquisition (by Joshi, P., Yu, K.N., Serbinowski, E., and Lee, M.Y.)
- Chapter 7. High-content image analysis (by Yu, S., Joshi, P., Lee, D.W., and Lee, M.Y.)
- Chapter 8. Applications of microarray bioprinting (by Roth, A.D., Serbinowski, E., and Lee, M.Y.)


- Patents
18. Lee, M.Y. and Sun, X.L., Multiplexed immune cell assays on a micropillar/microwell chip platform, Provisional Patent Application No. 62/570965 (Pending 2017)
17. Lee, M.Y., Chip platforms for microarray 3D bioprinting, Serial No. 15/816,485 and PCT/US17/62266 (Pending 2017)
16. Lee, M.Y., 3D-printed miniature biological constructs, Serial No. 15/404,291 and PCT/US17/13144 (Pending 2017)
15. Lee. M.Y., Jeong, S.H., Ku, B.S., Cell chips, US 20140273053 A1 (Pending 2014)
14. Lee, M.Y., Song, S.H., Lee, D.W., Jeong, S.H., and Ku, B.S., Apparatus for analyzing biomaterial, US 20140154722 A1 (Pending 2014)
13. Lee, D.W., Ku, B.S., Kim, S.J., and Lee, M.Y., Cell perfusion chip, US20140045256 A1 (Pending 2014)
12. Kim, S.J., Song, S.H., Ku, B.S., and Lee. M.Y., Fluid discharging device and method, US 20140227145 A1 (Pending 2014)
11. Kim, S.J., Song, S.H., Ku, B.S., and Lee, M.Y., Micro droplet discharging apparatus WO 2012158875 A1 (Pending 2012)
10. Jeon, S.Y., Ku, B.S., Ramachandran, S.K., and Lee. M.Y., Apparatus and method for analyzing data of cell chips, WO 2012125906 A1 (Pending 2012)
9. Song, S.H., Ku, B.S., Jeong, S.H., Lee, M.Y., Lee, D.W., Cell chip, US 20120165224 A1 (Pending 2012)
8. Lee. M.Y., Lee, D.W., Jeong, S.H., Yang, J.S. and Ku, B.S., Microarray cell chip, US 20120088693 A1 (Pending 2012)
7. Lee. M.Y., Kwon, S.J., Dordick, J.S., Clark D.S., and Ryan, J., Method of nucleic acid delivery into three-dimensional cell culture arrays, US 20110190162 A1 (Pending 2011)
6. Clark, D.S., Dordick, J.S., Traylor, M., Ryan, J., Lee, M.Y. and Sukumaran, S.M., Real time high-throughput method and apparatus for determining metabolic stability of compounds, PCT Int. Appl. (UC case number B10-018, Pending 2009)
5. Sharfstein, S., Zhang, H.Y. and Lee. M.Y., Gene delivery in three-dimensional cell cultures by superparamagnetic nanoparticles, PCT Int. Appl. (EFS ID: 6188827, Pending 2009)
4. Lee, M.Y., Ramasubramanian, A.K., Clark D.S. and Dordick, J.S., Three-dimensional cellular array chip and platform for toxicology assays, WO 2007053561 (Issued 2007)
3. Dordick, J.S., Lee, M.Y., Srinivasan, A., and Ku, B.S., Enzyme immobilization for electro-osmotic flow, US Patent 7,172,682 (Issued 2007)
2. Lee, M.Y., Synthesis of surface-active enzyme and its applications for interfacial reaction, Korea Patent 10-0540212 (Issued 2005)
1. Yang, J.W., Lee, M.Y. and Choi, K.Y., Chitin/chitosan-based surfactant and manufacturing method therefor, Korea Patent 10-0302158 (Issued 2001)